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dc.contributor.authorPelit, Emel
dc.contributor.authorOikonomou, Kosmas
dc.contributor.authorGül, Melek
dc.contributor.authorGeorgiou, Dimitra
dc.contributor.authorSzafert, Slawomir
dc.contributor.authorKatsamakas, Sotirios
dc.contributor.authorElemes, Yiannis
dc.date.accessioned2021-12-12T17:02:34Z
dc.date.available2021-12-12T17:02:34Z
dc.date.issued2017
dc.identifier.issn1631-0748
dc.identifier.issn1878-1543
dc.identifier.urihttps://doi.org/10.1016/j.crci.2016.05.024
dc.identifier.urihttps://hdl.handle.net/20.500.11857/3490
dc.description.abstractTriazolinedione quenches efficiently the 1,2-dipoles from Schiff bases of glycine esters which are formed via a [1,2-H]-prototropic shift of their alpha-hydrogens, and affords the respective alpha-aminated products in good yields. Competition experiments show a stabilization of the 1,2-dipole from the sulfide substituent. 5-exo-trig cyclization of N-PhTAD with Schiff bases of other amino acids gave triazolines. The antioxidative and lipoxygenase inhibitory activities of the novel synthesized compounds were studied. (C) 2016 Academie des sciences. Published by Elsevier Masson SAS. All rights reserved.en_US
dc.language.isoengen_US
dc.publisherElsevier France-Editions Scientifiques Medicales Elsevieren_US
dc.relation.ispartofComptes Rendus Chimieen_US
dc.identifier.doi10.1016/j.crci.2016.05.024
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectTriazolinedioneen_US
dc.subjectAmino aciden_US
dc.subjectSchiff baseen_US
dc.subject1,2-Dipoleen_US
dc.subjectalpha-Aminationen_US
dc.subject5-exo-trig cyclizationen_US
dc.titlealpha-Amination and the 5-exo-trig cyclization reaction of sulfur-containing Schiff bases with N-phenyltriazolinedione and their anti-lipid peroxidation activityen_US
dc.typearticle
dc.authoridKatsamakas, Sotirios/0000-0001-8715-0359
dc.authoridGul, Melek/0000-0002-0037-1202
dc.authoridPelit, Emel/0000-0002-5717-7355
dc.authoridSzafert, Slawomir/0000-0002-0570-8847
dc.departmentFakülteler, Fen-Edebiyat Fakültesi, Kimya Bölümü
dc.identifier.volume20en_US
dc.identifier.startpage424en_US
dc.identifier.issue4en_US
dc.identifier.endpage434en_US
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanıen_US
dc.authorscopusid16203801600
dc.authorscopusid56662872200
dc.authorscopusid23978054400
dc.authorscopusid55151726400
dc.authorscopusid6603538337
dc.authorscopusid15843840500
dc.authorscopusid35458544700
dc.identifier.wosWOS:000400656200012en_US
dc.identifier.scopus2-s2.0-85003680909en_US
dc.authorwosidKatsamakas, Sotirios/M-1530-2015
dc.authorwosidGul, Melek/A-1128-2013


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