Short-term effect of particular matter and sulfur dioxide exposure on asthma and/or chronic obstructive pulmonary disease hospital admissions in Center of Anatolia

Abstract

We investigated the associations between the daily variations of coarse particulate matter (PM10) and/or sulfur dioxide (SO2) and hospital admissions for asthma and/or chronic obstructive pulmonary disease (COPD) diseases in Kirsehir, Center of Anatolia of Turkey. We analyzed the poison generalized linear model (GLM) to analyze the association between ambient air pollutants such as PM(10)and SO(2)and asthma and/or COPD admissions. We investigated single-lag days and multi-lag days for the risk increase in asthma, COPD, asthma, and/or COPD hospital admissions PM10, SO2, and PM(10)with SO(2)per 10 mu g/m(3). In single-lag day model a 10 mu g/m(3)increase in the current day (lag 0) concentrations of PM(10)and SO(2)corresponded to increase of 1.027 (95% CI:1.022-1.033) and 1.069 (95% CI:1.062, 1.077) for asthma. A 10 mu g/m(3)increase in the current day (lag 0) concentrations of PM(10)and SO(2)corresponded to increase of 1.029 (95% CI:1.022-1.035) and 1.065 (95% CI:1.056, 1.075) for COPD. A 10 mu g/m(3)increase in the current day (lag 0) concentrations of PM(10)and SO(2)corresponded to increase of 1.028 (95% CI:1.024-1.032) and 1.068 (95% CI:1.062, 1.074) for asthma and/or COPD. It was found that some lag structures were related with PM(10)and SO2. Significant lags were detected in some lag structures from the previous first day until the previous eighth day (lag 1 to lag 7) in the asthma, COPD, and asthma and/or COPD hospital admissions in the model created with PM(10)with SO(2)both in the single-lag day model and in the multi-lag day model. Our study that used GLM in time series analysis showed that PM(10)and/or SO(2)short-term exposure in single-lag day and multi-lag day models was related with increased asthma, COPD, and asthma and/or COPD hospital admissions in the city between 2016 and 2019 until the previous-eighth day.