Browsing by Author "Korkmaz, Gülcan Güntaş"
Now showing items 1-9 of 9
-
The association of lectin-like oxidized LDL receptor 1 (LOX-1) K167N and 3'UTR188CT polymorphisms with maternal plasma soluble LOX-1 levels and preeclampsia risk in Turkish population
Tüten, Abdullah; Aydemir, Birsen; Öncül, Mahmut; Kızıler, Ali Rıza; Açıkgöz, Abdullah Serdar; Korkmaz, Gülcan Güntaş; Uzun, Hafize (Springer Heidelberg, 2015)To investigate the main effect of polymorphisms in genes involved in endothelial pathophysiological mechanisms, LOX-1 K167N and 3'UTR188CT single nucleotide polymorphisms (SNPs) in relation to preeclampsia (PE) risk and ... -
The association of oxidative stress markers with conventional risk factors in the metabolic syndrome
Korkmaz, Gülcan Güntaş; Altınoğlu, Esma; Civelek, Sabiha; Sözer, Volkan; Erdenen, Füsun; Tabak, Omur; Uzun, Hafize (W B Saunders Co-Elsevier Inc, 2013)Background and Aims. The metabolic syndrome (MetS) is a common and complex disorder that consists of various abnormalities, including dyslipidemia, obesity, hypertension and hyperglycemia. We investigated the relationships ... -
The effects on oxidative DNA damage of laparoscopic gastric band applications in morbidly obese patients
Kocael, Ahmet; Erman, Hayriye; Zengin, Kagan; Kocael, Pınar Çiğdem Arica; Korkmaz, Gülcan Güntaş; Gelisgen, Remise; Uzun, Hafize (Cma-Canadian Medical Assoc, 2014)Background: Obesity may induce oxidative stress, causing oxidative damage of DNA. We examined associations between decreasing serum and urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels and weight loss in morbidly obese ... -
Evaluation of Serum Paraoxonase and Arylesterase Activities in Subjects with Asthma and Chronic Obstructive Lung Disease
Acay, A.; Erdenen, Füsun; Altunoğlu, E.; Erman, H.; Muderrisoğlu, C.; Korkmaz, Gülcan Güntaş; Uzun, Hafize (Clin Lab Publ, 2013)Background: Asthma and chronic obstructive lung disease (COPD) are characterised by airway inflammation. Paraoxonase1 (PON1) and arylesterase (AE) enzymes have the ability to protect HDL from oxidation and may have ... -
Ischemia-modified albumin and advanced oxidation protein products as potential biomarkers of protein oxidation in Alzheimer's disease
Altunoğlu, E.; Korkmaz, Gülcan Güntaş; Erdenen, Füsun; Akkaya, E.; Topaç, I.; Irmak, H.; Uzun, Hafize (Blackwell Publishing, 2015)Background: The aim of the present study was to determine the systemic levels of oxidative stress markers, such as ischemia-modified albumin (IMA), advanced oxidation protein products (AOPP), ferric reducing antioxidant ... -
Melatonin ameliorates oxidative damage in hyperglycemia-induced liver injury
Korkmaz, Gülcan Güntaş; Uzun, Hafize; Cakatay, Ufuk; Aydın, Seval (Canadian Soc Clinical Investigation, 2012)Purpose: Melatonin (N-acetyl-5-methoxy-tryptamine) is synthesized mainly by the pineal gland and its antioxidant properties have been demonstrated both in short and long term studies. Our aim was to clarify the effects of ... -
Oxidative damage parameters in renal tissues of aged and young rats based on gender
Uzun, Duygu; Korkmaz, Gülcan Güntaş; Sitar, Mustafa Erinc; Cebe, Tamer; Yanar, Karolin; Cakatay, Ufuk; Aydın, Seval (Dove Medical Press Ltd, 2013)Purpose: Aging is characterized by a gradual functional decrease of all systems including the kidneys. Growing evidence links altered lipid protein redox-homeostasis with renal dysfunction. The effect of sexual dimorphism ... -
The role of pentraxin 3 as diagnostic value in classification of patients with heart failure
Duran, Sermin; Duran, İlyas; Kaptanağası, Fatma Asuman Orçun; Nartop, Filiz; Çiftçi, Hilmi; Korkmaz, Gülcan Güntaş (Pergamon-Elsevier Science Ltd, 2013)Objective: Pentraxin 3 (PTX3) is a new inflammatory marker that is the prototype of the long pentraxin group, while C-reactive protein (CRP) is the short pentraxin group. The aim of the present study was to investigate the ... -
Total antioxidant status and markers of oxidative stress in subjects with normal or impaired glucose regulation (IFG, IGT) in diabetic patients
Korkmaz, Gülcan Güntaş; Konukoğlu, Dildar; Kurtuluş, Eda Merve; Irmak, Hülya; Bolayırlı, Murat; Uzun, Hafize (Taylor & Francis Ltd, 2013)Background. We investigated the ischemia-modified albumin (IMA), advanced oxidation protein products (AOPPs), prooxidants - antioxidants balance (PAB), and ferric reducing antioxidant power (FRAP) concentrations in patients ...