Bölüm "Fakülteler, Tıp Fakültesi, Temel Tıp Bilimleri, Tıbbi Biyokimya Anabilim Dalı" için listeleme
Toplam kayıt 16, listelenen: 1-16
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The association of lectin-like oxidized LDL receptor 1 (LOX-1) K167N and 3'UTR188CT polymorphisms with maternal plasma soluble LOX-1 levels and preeclampsia risk in Turkish population
(Springer Heidelberg, 2015)To investigate the main effect of polymorphisms in genes involved in endothelial pathophysiological mechanisms, LOX-1 K167N and 3'UTR188CT single nucleotide polymorphisms (SNPs) in relation to preeclampsia (PE) risk and ... -
The association of oxidative stress markers with conventional risk factors in the metabolic syndrome
(W B Saunders Co-Elsevier Inc, 2013)Background and Aims. The metabolic syndrome (MetS) is a common and complex disorder that consists of various abnormalities, including dyslipidemia, obesity, hypertension and hyperglycemia. We investigated the relationships ... -
Comparison of maternal and umbilical cord blood soluble lectin-like oxidized low-density lipoprotein receptor 1 levels in early-and late-onset preeclampsia
(Springer Heidelberg, 2014)Background The main purpose of this study was to determine the maternal and umbilical cord blood oxidized LDL (oxLDL) and soluble lectin-like oxidized low-density lipoprotein receptor-1 (sLOX-1) levels in early-and late-onset ... -
The effect of chronic long-term intermittent hypobaric hypoxia on bone mineral density in rats: Role of nitric oxide
(2013)Intermittent hypoxia is the most common pattern of hypoxic exposure in humans. The effect of chronic long-term intermittent hypobaric hypoxia (CLTIHH) on bone metabolism is not investigated. We examined the effect of CLTIHH ... -
The effects on oxidative DNA damage of laparoscopic gastric band applications in morbidly obese patients
(Cma-Canadian Medical Assoc, 2014)Background: Obesity may induce oxidative stress, causing oxidative damage of DNA. We examined associations between decreasing serum and urinary 8-hydroxy-2'-deoxyguanosine (8-OHdG) levels and weight loss in morbidly obese ... -
Evaluation of Serum Paraoxonase and Arylesterase Activities in Subjects with Asthma and Chronic Obstructive Lung Disease
(Clin Lab Publ, 2013)Background: Asthma and chronic obstructive lung disease (COPD) are characterised by airway inflammation. Paraoxonase1 (PON1) and arylesterase (AE) enzymes have the ability to protect HDL from oxidation and may have ... -
Ischemia-modified albumin and advanced oxidation protein products as potential biomarkers of protein oxidation in Alzheimer's disease
(Blackwell Publishing, 2015)Background: The aim of the present study was to determine the systemic levels of oxidative stress markers, such as ischemia-modified albumin (IMA), advanced oxidation protein products (AOPP), ferric reducing antioxidant ... -
Melatonin ameliorates oxidative damage in hyperglycemia-induced liver injury
(Canadian Soc Clinical Investigation, 2012)Purpose: Melatonin (N-acetyl-5-methoxy-tryptamine) is synthesized mainly by the pineal gland and its antioxidant properties have been demonstrated both in short and long term studies. Our aim was to clarify the effects of ... -
Oxidative damage parameters in renal tissues of aged and young rats based on gender
(Dove Medical Press Ltd, 2013)Purpose: Aging is characterized by a gradual functional decrease of all systems including the kidneys. Growing evidence links altered lipid protein redox-homeostasis with renal dysfunction. The effect of sexual dimorphism ... -
Paraoxonase, oxidized low density lipoprotein, monocyte chemoattractant protein-1 and adhesion molecules are associated with macrovascular complications in patients with type 2 diabetes mellitus
(Edizioni Minerva Medica, 2014)Aim. The aim of this paper was to evaluate the association between blood glucose, oxidative stress, inflammation, endothelial dysfunction and paraoxonase activity as contributors to the accelerated atherosclerosis seen in ... -
The Relationship between Ischemia Modified Albumin and Oxidative Stress Parameters in Patients with Cardiac Syndrome X
(Clin Lab Publ, 2013)Background: The objective of this study was to evaluate the serum levels of ischemia modified albumin and oxidative stress parameters in patients with cardiac syndrome X. Methods: A total of 61 patients, composed of 32 ... -
THE ROLE OF CHITOTRIOSIDASE ACTIVITY AS A PROGNOSTIC BIOMARKER IN SARCOIDOSIS
(Carbone Editore, 2015)Introduction: Chitotriosidase (ChT) is a chitinase that is massively expressed by lipid-laden tissue macrophages in human beings. The aim of this study was to compare ChT activities in the serum and bronchoalveolar lavage ... -
The role of feed regulating peptides on weight loss in patients with pulmonary tuberculosis
(Pergamon-Elsevier Science Ltd, 2013)Purpose: Malnutrition is a prominent feature of tuberculosis (TB). The aim of our study was to explore the function of plasma regulatory proteins in pulmonary TB and to investigate the relationship between these parameters ... -
The role of pentraxin 3 as diagnostic value in classification of patients with heart failure
(Pergamon-Elsevier Science Ltd, 2013)Objective: Pentraxin 3 (PTX3) is a new inflammatory marker that is the prototype of the long pentraxin group, while C-reactive protein (CRP) is the short pentraxin group. The aim of the present study was to investigate the ... -
Serum Thymidine Kinase 1 Activity in Solid Tumor (Breast and Colorectal Cancer) Patients Treated With Adjuvant Chemotherapy
(Wiley, 2013)BackgroundThe aim of this study was to evaluate the changing of TK1 (where TK is thymidine kinase) activity before and after adjuvant chemotherapy in patients with breast and colorectal cancer. MethodsThe study included ... -
Total antioxidant status and markers of oxidative stress in subjects with normal or impaired glucose regulation (IFG, IGT) in diabetic patients
(Taylor & Francis Ltd, 2013)Background. We investigated the ischemia-modified albumin (IMA), advanced oxidation protein products (AOPPs), prooxidants - antioxidants balance (PAB), and ferric reducing antioxidant power (FRAP) concentrations in patients ...